Posted in Government & Military, Information Technology, Pop Culture, Science DS2 stands for Dark Souls 2 (gaming) DS2 stands for Dead Space 2 (gaming) DS2 stands for Dualshock 2 (gamepads) DS2 stands for Dungeon Siege 2 (video game) DS2 stands for Design of Systems on Silicon DS2 stands for Defense Support Services (Lockheed Martin/Day Zimmermann) DS2 stands for Deca Sports 2 (game) DS2 stands for Digital Signal 2 – (6.54 Mbps Pipe)