- DPE stands for Diagnostic de Performance Énergétique (French: Energy Performance Certificate)
- DPE stands for Directorate of Primary Education (various locations)
- DPE stands for Direction de la Propreté et de l’Eau (French: Branch and Clean Water)
- DPE stands for Division des Personnels Enseignants (French:Teaching Staff Division)
- DPE stands for Digital Preservation Europe
- DPE stands for Department of Public Enterprises (India)
- DPE stands for Designated Pilot Examiner (conducts FAA checkrides)
- DPE stands for Diplômé par l’Etat (French degree)
- DPE stands for Double Pomeron Exchange
- DPE stands for Division de la Police de l’Environnement (French: Police Division of the Environment; Belgium)
- DPE stands for Distributed Processing Environment
- DPE stands for Department of Physical Education (formerly Office of Physical Education; US Military Academy)
- DPE stands for Dual-Phase Extraction (DNAPL removal system)
- DPE stands for Department of Planning and Economy (Abu Dhabi, United Arab Emirates)
- DPE stands for Dynamic Programming Equation
- DPE stands for Direction des Personnels Enseignants (French: Management of Teaching Staff; various universities)
- DPE stands for Direct Personnel Expense
- DPE stands for Dynamisme Presse Édition (French: Dynamic Edition Press)
- DPE stands for Delta Pi Epsilon (national honorary graduate society; est. 1936)
- DPE stands for Downstream Promoter Element (nucleotide core promoter element)
- DPE stands for Department of Postsecondary Education
- DPE stands for Data Processing Equipment
- DPE stands for Disease Prevention Education
- DPE stands for Dipivefrin (anti-glaucoma medicine)
- DPE stands for DELMIA Process Engineer
- DPE stands for Des Produits Efficaces (French: Efficient Products)
- DPE stands for Demonstrator in Physical Education (India)
- DPE stands for Développement Post Embryonnaire (French: Post Embryonic Development)
- DPE stands for Disk Processor Enclosure
- DPE stands for Developmental Psychology Education