- CASE stands for Council for Advancement and Support of Education
- CASE stands for Computer-Aided Software Engineering
- CASE stands for Center for Social and Economic Research (Poland)
- CASE stands for Compressed Air System
- CASE stands for Consumers Association of Singapore (nonprofit consumer protection agency)
- CASE stands for Centre for Analysis of Social Exclusion (UK)
- CASE stands for Council of American Structural Engineers
- CASE stands for Center for Advanced Studies In Engineering (Pakistan)