Posted in Health & Medicine, Internet Slang, Science, Sports YDB stands for Younger Dryas Boundary (hypothesis) YDB stands for Yucky Discolored Box Syndrome (Adobe InDesign problem) YDB stands for Yokohama Dena Baystars (Japanese baseball team) YDB stands for You Deserve Better YDB stands for Yeah da Boys YDB stands for Youth Design Boston (summer internship and mentoring program; Boston, MA) YDB stands for You Dumb Bastard YDB stands for Yeast Dextrose Broth (microbiology) YDB stands for Yeat da Bun (commonly used in the town of Newburyport, MA) YDB stands for Yield Difference Bonding