- XBT stands for Bitcoin (cryptocurrency)
- XBT stands for Expendable Bathythermograph
- XBT stands for Crossbar Tandem
- XBT stands for Xenon Beacon Tracker
- XBT stands for X-ray Backscatter Technology
- XBT stands for Crossbraced Truss
- XBT stands for 14C-D-Xylose Breath Test (diagnostics)